Biorbyt's CD163 antibody is a Mouse monoclonal antibody. The CD163 antibody was generated using CD163 as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Precipitation, Flow Cytometry, Immunohistochemistry, Immunohistochemistry - frozen, Immunoprecipitation, and Western Blot.
Description
Mouse monoclonal to CD163. CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold